Weight Loss on GLP-1s

Section

Training

5 pages in this section, most recently updated September 4, 2026. Each opens with a plain-English summary and cites its sources.

  1. 01 · Training

    Featured

    Resistance training on a GLP-1: the minimum that works, how to start, and how to progress

    You'll get: Guidelines ask for strength work on two or more days a week. The 2025 GLP-1 advisory asks for three.

    What the physical activity guidelines and the 2025 joint advisory ask for, what the meta-analyses show about protein plus lifting, a two-to-three-day starting programme with progression rules, and the safety notes specific to therapy.

    Updated September 4, 2026
    Paper-cut illustration of a folded map with a dotted route and a small start flag

  2. 02 · Training

    Fat versus lean: what the STEP 1 and SURMOUNT-1 DXA substudies actually measured

    You'll get: In the trial scans, about a quarter to two-fifths of the weight lost was lean tissue, not fat.

    The body-composition numbers from the semaglutide and tirzepatide pivotal trials, what share of the weight lost was lean tissue, how that compares with other weight loss, what lean mass includes, and what the evidence says changes the ratio.

    Updated September 4, 2026

  3. 03 · Training

    Exercising when nauseated: what to keep, what to drop, and when to stop

    You'll get: Nausea hits 44 percent of people on the top semaglutide dose, mostly in the days after each dose increase.

    Nausea is the most common adverse reaction on GLP-1 therapy and clusters around dose escalation. How to keep training through it without making it worse, the hydration and glucose warnings that apply, and the symptoms that mean stop and call.

    Updated September 4, 2026

  4. 04 · Training

    Aerobic activity and daily steps: the guideline numbers, the step-count evidence, and what the trials asked

    You'll get: Guidelines ask for 150 to 300 minutes a week of moderate activity plus strength work on two or more days.

    The 150 to 300 minute guideline and where it comes from, the 2022 meta-analysis on daily steps and mortality, why aerobic exercise alone does not protect lean mass, and how to fit it around a GLP-1's side effects.

    Updated September 4, 2026

  5. 05 · Training

    Exercise plus a GLP-1: what the randomised trials show, and what nobody has tested yet

    You'll get: One trial combined a GLP-1 with supervised exercise for a year. Drug and exercise together held more weight off than either alone.

    S-LiTE, the only large randomised trial to combine a GLP-1 with a structured exercise programme, Villareal's trial of exercise type during weight loss, what they show about additive effects and body composition, and the gaps that remain for semaglutide and tirzepatide.

    Updated September 4, 2026